JNJ-40411813

Ligand id: 8946

Name: JNJ-40411813

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 23.55
Molecular weight 344.17
XLogP 6.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-2(1H)-pyridinone
Synonyms
ADX71149 | JNJ 40411813
Database Links
CAS Registry No. 1127498-03-6 (source: PubChem)
PubChem CID 25195461
Search Google for chemical match using the InChIKey HYOGJHCDLQSAHX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HYOGJHCDLQSAHX
Search UniChem for chemical match using the InChIKey HYOGJHCDLQSAHX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HYOGJHCDLQSAHX
Comments
JNJ-40411813 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 2 (mGlu2) [1].