PF-152

Ligand id: 9014

Name: PF-152

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 146.4
Molecular weight 473.18
XLogP 0.68
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(4-fluoro-3-methoxyphenyl)methyl]-6-[2-[[(2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl]methyl]tetrazol-5-yl]-2-methylpyrimidine-4-carboxamide
Synonyms
compound 43a [1] | example 64 [WO2009016498] [2] | PF152
Database Links
PubChem CID 25183622
Search Google for chemical match using the InChIKey SKEAGJWUKCNICJ-LSDHHAIUSA-N
Search Google for chemicals with the same backbone SKEAGJWUKCNICJ
Search UniChem for chemical match using the InChIKey SKEAGJWUKCNICJ-LSDHHAIUSA-N
Search UniChem for chemicals with the same backbone SKEAGJWUKCNICJ
Comments
PF-152 is a matrix metalloproteinase-13 (MMP13) inhibitor [1], with potential to treat osteoarthritis.