AZ10606120

Ligand id: 9021

Name: AZ10606120

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 10
Topological polar surface area 86.28
Molecular weight 422.27
XLogP 4.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(1-adamantyl)-N-[2-[2-(2-hydroxyethylamino)ethylamino]quinolin-5-yl]acetamide
Synonyms
AZ 10606120 | AZ-10606120 | compound 43 [PMID: 19191585] | compound-17 [PMID: 18071294] [3]
Database Links
BindingDB Ligand 50414283
ChEMBL Ligand CHEMBL562308
GtoPdb PubChem SID 315661106
PubChem CID 10310632
Search Google for chemical match using the InChIKey FQMZXMVHHKXGTM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FQMZXMVHHKXGTM
Search UniChem for chemical match using the InChIKey FQMZXMVHHKXGTM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FQMZXMVHHKXGTM
Comments
AZ10606120 is a negative allosteric modulator of the human P2X7 receptor [3-4]. As a research compound AZ10606120 is being studied for its potential antineoplastic activity [1].