INCB3284

Ligand id: 9045

Name: INCB3284

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 103.79
Molecular weight 520.23
XLogP 3.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide
Synonyms
compound 13 [PMID: 24900329] | INCB 3284
Database Links
CAS Registry No. 887401-92-5 (source: PubChem)
PubChem CID 11527661
Search Google for chemical match using the InChIKey NXZNYBUBXWWKCP-JMOWIOHXSA-N
Search Google for chemicals with the same backbone NXZNYBUBXWWKCP
Search UniChem for chemical match using the InChIKey NXZNYBUBXWWKCP-JMOWIOHXSA-N
Search UniChem for chemicals with the same backbone NXZNYBUBXWWKCP
Comments
INCB3284 is a potent, selective and orally available small molecule antagonist of the chemokine (C-C motif) receptor 2 (CCR2) [1], developed for potential anti-inflammatory activity. Note that alternative isomeric forms of this compound are presented by different online resources (e.g. CHEMBL1963131 and CHEMBL1951790).