PF-04995274

Ligand id: 9059

Name: PF-04995274

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 86.42
Molecular weight 432.23
XLogP 1.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Synonyms
compound 2d [PMID: 22974325] | PF 04995274 | PF04995274
Database Links
BindingDB Ligand 50398598
CAS Registry No. 1331782-27-4 (source: PubChem)
ChEMBL Ligand CHEMBL2152922
PubChem CID 53354764
Search Google for chemical match using the InChIKey WLLOFQROROXOMO-GOSISDBHSA-N
Search Google for chemicals with the same backbone WLLOFQROROXOMO
Search UniChem for chemical match using the InChIKey WLLOFQROROXOMO-GOSISDBHSA-N
Search UniChem for chemicals with the same backbone WLLOFQROROXOMO
Comments
PF-04995274 is a serotonin 5-HT4 receptor partial agonist, developed as a potential pro-cognitive agent for the treatment of Alzheimer's disease (AD) [1].