PF-03882845

Ligand id: 9061

Name: PF-03882845

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 76.69
Molecular weight 419.14
XLogP 5.81
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydrobenzo[g]indazole-7-carboxylic acid
Synonyms
compound 2 [PMID: 24738581] | PF-3882845
Database Links
BindingDB Ligand 50324210
CAS Registry No. 1023650-66-9 (source: PubChem)
ChEMBL Ligand CHEMBL1215331
PubChem CID 46871935
Search Google for chemical match using the InChIKey XNULRSOGWPFPBL-REWPJTCUSA-N
Search Google for chemicals with the same backbone XNULRSOGWPFPBL
Search UniChem for chemical match using the InChIKey XNULRSOGWPFPBL-REWPJTCUSA-N
Search UniChem for chemicals with the same backbone XNULRSOGWPFPBL
Comments
PF-03882845 is an investigational, potent and selective, non-steroidal mineralocorticoid receptor antagonist [2], with potential protective effect in aldosterone-mediated renal damage (nephropathy).