flortaucipir (18F)

Ligand id: 9100

Name: flortaucipir (18F)    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 41.57
Molecular weight 263.09
XLogP 3.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
7-(6-fluoranylpyridin-3-yl)-5H-pyrido[4,3-b]indole
International Nonproprietary Names
INN number INN
10203 flortaucipir (18F)
Synonyms
18F-AV-1451
[F-18]T807
flortaucipir F-18
LY-3191748
Database Links
CAS Registry No. 1522051-90-6 (source: WHO INHN record)
ChEMBL Ligand CHEMBL3545253
PubChem CID 70957463
Search Google for chemical match using the InChIKey GETAAWDSFUCLBS-SJPDSGJFSA-N
Search Google for chemicals with the same backbone GETAAWDSFUCLBS
Search PubMed clinical trials flortaucipir
Search PubMed titles flortaucipir
Search PubMed titles/abstracts flortaucipir
Comments
Flortaucipir (18F) is an investigational PET imaging agent (diagnostic radiopharmaceutical) designed to visualise tau protein (MAPT; P10636) in Alzheimer's disease brains. Compare with the approved agent, florbetapir, used to visualise β-amyloid.