SC-22716

Ligand id: 9102

Name: SC-22716

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 12.47
Molecular weight 267.16
XLogP 6.15
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine
Synonyms
SC 22716
Database Links
BindingDB Ligand 50085251
CAS Registry No. 262451-89-8 (source: PubChem)
ChEMBL Ligand CHEMBL119054
PubChem CID 10333202
Search Google for chemical match using the InChIKey PKUGRVAJRGZDJP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PKUGRVAJRGZDJP
Search UniChem for chemical match using the InChIKey PKUGRVAJRGZDJP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PKUGRVAJRGZDJP
Comments
SC-22716 is an experimental leukotriene A4 hydrolase inhibitor. It was the primary lead for the SAR study reported in [1]. SC-22716 acts as a potent, competitive and reversible inhibitor of the hydrolase and peptidase activities of human leukotriene A4 hydrolase.