glesatinib

Ligand id: 9133

Name: glesatinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 141.4
Molecular weight 517.1
XLogP 6.53
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-phenylacetamide
International Nonproprietary Names
INN number INN
10217 glesatinib
Synonyms
compound 10a [PMID: 18434145] | MGCD 265 | MGCD-265 | MGCD265
Database Links
BindingDB Ligand 24498
ChEMBL Ligand CHEMBL254760
PubChem CID 24901704
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Comments
Glesatinib is an orally available Met/VEGFR kinase inhibitor.