BMS-986122

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Ligands
BMS-986122

Ligand id: 9157

Name: BMS-986122

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	4
Topological polar surface area	80.29
Molecular weight	446.94
XLogP	4.31
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
2-(3-bromo-4-methoxyphenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine

IUPAC Name

2-(3-bromo-4-methoxyphenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine

Database Links
GtoPdb PubChem SID	315661241
PubChem CID	4644453
Search Google for chemical match using the InChIKey	PNGJPVDGZNPZHY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	PNGJPVDGZNPZHY
Search UniChem for chemical match using the InChIKey	PNGJPVDGZNPZHY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	PNGJPVDGZNPZHY

Comments
BMS-986122 is a positive allosteric modulator (PAM) of the μ opioid receptor [3]. It is one of the compounds claimed in patent WO2014107344 [2]. BMS-986122 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs [1].

Comments

BMS-986122 is a positive allosteric modulator (PAM) of the μ opioid receptor [3]. It is one of the compounds claimed in patent WO2014107344 [2]. BMS-986122 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs [1].