zyklophin

Ligand id: 9193

Name: zyklophin

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Peptide or derivative
Comments
Zyklophin is a cyclic analogue of dynorphin A-(1−11) with antagonist action selective for the κ opioid receptor. Structure, synthesis and function is described in [2], where it is peptide 2. The peptide is brain-penetrant, and has a relatively short duration of action compared to established small-molecule selective KOR antagonists such as nor-binaltorphimine [1].
Database Links
BindingDB Ligand 50299408
ChEMBL Ligand CHEMBL574568
GtoPdb PubChem SID 315661272
PubChem CID 45483651
Search Google for chemical match using the InChIKey UWLIKQFWZOPOAX-HRFULILYSA-N
Search Google for chemicals with the same backbone UWLIKQFWZOPOAX
Search UniChem for chemical match using the InChIKey UWLIKQFWZOPOAX-HRFULILYSA-N
Search UniChem for chemicals with the same backbone UWLIKQFWZOPOAX
Wikipedia Zyklophin