Compound class:
Synthetic organic
Comment: The discovery of the so-called STING agonist G10 by high throughput in vitro screening is reported in [1]. However, the authors could find no evidence of direct G10 binding to STING, despite experiments showing it being essential for the antiviral effects of the compound. The identity of the protein or factor engaged by G10 which stimulates the STING-dependent response is still being investigated.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
4-[(2-chloro-6-fluorophenyl)methyl]-N-(furan-2-ylmethyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxamide |
Database Links | |
GtoPdb PubChem SID | 315661282 |
PubChem CID | 5077622 |
Search Google for chemical match using the InChIKey | NAGKYJATVFXZKN-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | NAGKYJATVFXZKN |
UniChem Compound Search for chemical match using the InChIKey | NAGKYJATVFXZKN-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NAGKYJATVFXZKN-UHFFFAOYSA-N |
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G10 (links to external site)
Cat. No. 5944 |