peptide 30 [PMID: 27019010]

Ligand id: 9253

Name: peptide 30 [PMID: 27019010]

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Peptide or derivative
IUPAC Name
methyl (2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoate
Comments
Peptide 30 is a synthetic tetrapeptide reported to occupy the arachadonic acid binding site of cyclooxygenase 2 (COX-2) to bring about enzyme inhibition with an antiinflammatory/analgesic outcome [1]. Docking studies suggest that peptide 30 can occupy the active site of inducible nitric oxide synthase (iNOS; iNOS being well documented in pain mechanisms), although the COX-2 interaction is considered to be the major contributor to both the analgesic and antiinflammatory effects of the peptide in vivo.
Database Links
GtoPdb PubChem SID 315661328
PubChem CID 11750118
Search Google for chemical match using the InChIKey CSHFHJNMIMPJST-HOTGVXAUSA-N
Search Google for chemicals with the same backbone CSHFHJNMIMPJST
Search UniChem for chemical match using the InChIKey CSHFHJNMIMPJST-HOTGVXAUSA-N
Search UniChem for chemicals with the same backbone CSHFHJNMIMPJST