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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|compound 1b [PMID: 21866885]|
|BU08028 is a novel research compound that provides the pain relief of opiates, without their addictive effects in mouse models of acute pain and cocaine-induced reward [1-2]. Structurally it is a derivative of buprenorphine, with only the addition of an additional methylene group at the C20 substituent. Increasing affinity for the NOP receptor is predicted to reduce the behavioural side-effects associated with buprenorphine.
Note that the compound referred to as 1b in  has a marginally different stereo compared to the same compound (named as BUB8028) in , with identical data provided for 1b and BUB8028 in both articles. Compound 1b resolves to PubChem CID 56664973. We have chosen to link to CID 50922685 as the specified stereochemistry of this is identical to that of buprenorphine.
|GtoPdb PubChem SID||318164813|
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