|
Molecular properties generated using the CDK |
Classification ![]() |
|
Compound class | Synthetic organic |
IUPAC Name ![]() |
2-[2-(cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide |
Synonyms ![]() |
bipyridyl PKD inhibitor |
Comments |
BPKDi inhibits all three protein kinase D isozymes at low nanomolar concentrations [1]. This tool compound has been used to show that PKD acts to phosphorylate class IIa histone deacetylases in cardiomyocytes during cardiac hypertrophy. Inhibition of this action by BPKDi suppresses cardiomyocyte hypertrophy. |
Database Links ![]() |
|
BindingDB Ligand | 50324323 |
CAS Registry No. | 1201673-28-0 (source: PubChem) |
ChEMBL Ligand | CHEMBL1214999 |
GtoPdb PubChem SID | 328083472 |
PubChem CID | 46901383 |
Search Google for chemical match using the InChIKey | XNWDRALEEPGBHB-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | XNWDRALEEPGBHB |
Search UniChem for chemical match using the InChIKey | XNWDRALEEPGBHB-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | XNWDRALEEPGBHB |