OSI-930

Ligand id: 9383

Name: OSI-930

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 91.49
Molecular weight 443.09
XLogP 6.58
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
Synonyms
OSI 930 | OSI930
Database Links
BindingDB Ligand 50356877
ChEMBL Ligand CHEMBL1614710
PubChem CID 9868037
Search Google for chemical match using the InChIKey FGTCROZDHDSNIO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FGTCROZDHDSNIO
Search UniChem for chemical match using the InChIKey FGTCROZDHDSNIO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FGTCROZDHDSNIO
Comments
OSI-930 is a multi-targeted kinase inhibitor, with potent inhibitory activity vs. Kit, KDR, CSF-1R, Flt1, c-Raf and Lck [1].