SNS-314

Ligand id: 9397

Name: SNS-314

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 148.31
Molecular weight 430.04
XLogP 3.44
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(3-chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea
Synonyms
compound 21 [PMID: 18678489] | SNS314
Comments
SNS-314 is an inhibitor of Aurora kinases A and B [1]. CHEMBL482767 represents an alternative tautomer of the compound.
Database Links
BindingDB Ligand 26326
GtoPdb PubChem SID 328083499
PubChem CID 24995524
RCSB PDB Ligand AK2
Search Google for chemical match using the InChIKey FAYAUAZLLLJJGH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FAYAUAZLLLJJGH
Search UniChem for chemical match using the InChIKey FAYAUAZLLLJJGH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FAYAUAZLLLJJGH