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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|analog 49 (Dasse et al., 2007) |
|CCR2-RA-[R] is an allosteric antagonist of the CC chemokine receptor 2 (CCR2) . Allosteric modulation by CCR2-RA-[R] prevents formation of the G-protein-binding interface and hence G-protein coupling by blocking the required activation-associated changes in receptor conformation . The chemical structure presented here is that held with the PDB X-ray structure reported in .
CCR2-RA-[R] is claimed as chiral example 125 in patent US6936633 .
|GtoPdb PubChem SID||328083531|
|RCSB PDB Ligand||VT5|
|Search Google for chemical match using the InChIKey||VQNLJXWZGVRLBA-MRXNPFEDSA-N|
|Search Google for chemicals with the same backbone||VQNLJXWZGVRLBA|
|Search UniChem for chemical match using the InChIKey||VQNLJXWZGVRLBA-MRXNPFEDSA-N|
|Search UniChem for chemicals with the same backbone||VQNLJXWZGVRLBA|
|SynPHARM||84096 (in complex with CCR2)|