YM-244769

Ligand id: 9484

Name: YM-244769

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 86.47
Molecular weight 443.16
XLogP 5.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]pyridine-3-carboxamide
Synonyms
YM244769
Database Links
PubChem CID 244769
Search Google for chemical match using the InChIKey JZMLHJRKSJXARY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JZMLHJRKSJXARY
Search UniChem for chemical match using the InChIKey JZMLHJRKSJXARY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JZMLHJRKSJXARY
Comments
YM-244769 is a novel potent Na+/Ca2+ exchange (NCX) inhibitor, with selectivity for NCX3 (SLC8A3) over the other SLC8 family exchangers [1].