blisibimod

Ligand id: 9518

Name: blisibimod

Classification
Compound class Peptide or derivative
International Nonproprietary Names
INN number INN
9583 blisibimod
Synonyms
A-623 | AGP3 peptibody [5] | AMG 623 | Fc-Agp-3 [1]
Comments
Blisibimod is a peptibody fusion containing four BAFF binding domains fused to a human Fc domain. By sequestering circulating BAFF ligand, it acts as a functional antagonist of BAFF interaction with the TACI receptor on B cells.
Peptide sequences and structural information for this peptide are available from its IMGT/mAb-DB entry. The peptide sequence for blisibimod is claimed in Amgen's patent WO2002092620 [5].
Database Links
Specialist databases
IMGT/mAb-DB 413
Other databases
GtoPdb PubChem SID 336446905
Search PubMed clinical trials blisibimod
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