Classification
Compound class	Synthetic organic

IUPAC Name

5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile

International Nonproprietary Names
INN number	INN
10276	prexasertib

Synonyms

LY2606368

Comments

Prexasertib (LY2606368), an investigational small molecule checkpoint kinase 1 (CHK1) inhibitor [2] that exhibits anti-tumour activity in preclinical models of pediatric cancer.

Database Links
CAS Registry No.	1234015-52-1 (source: WHO INN record)
ChEMBL Ligand	CHEMBL3544911
GtoPdb PubChem SID	336446935
PubChem CID	46700756
Search Google for chemical match using the InChIKey	DOTGPNHGTYJDEP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	DOTGPNHGTYJDEP
Search PubMed clinical trials	prexasertib
Search PubMed titles	prexasertib
Search PubMed titles/abstracts	prexasertib
Search UniChem for chemical match using the InChIKey	DOTGPNHGTYJDEP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	DOTGPNHGTYJDEP