GLPG1690

Ligand id: 9561

Name: GLPG1690

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 132.48
Molecular weight 588.24
XLogP 2.72
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[[2-ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile
Synonyms
compound 11 [PMID: 28414242] | GLPG-1690
Database Links
CAS Registry No. 1628260-79-6 (source: PubChem)
ChEMBL Ligand CHEMBL3828074
PubChem CID 90420193
Search Google for chemical match using the InChIKey REQQVBGILUTQNN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone REQQVBGILUTQNN
Search UniChem for chemical match using the InChIKey REQQVBGILUTQNN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone REQQVBGILUTQNN
Comments
GLPG1690 is an autotaxin Inhibitor [2], being investigated for anti-fibrotic efficacy.