compound 8c [PMID: 28760529]

Ligand id: 9671

Name: compound 8c [PMID: 28760529]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 102.73
Molecular weight 417.11
XLogP 3.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
6-{[2-chloro-4-nitro-5-(oxan-4-yloxy)phenyl]amino}-3,4-dihydro-1H-quinolin-2-one
Database Links
GtoPdb PubChem SID 348353630
PubChem CID 131801156
Search Google for chemical match using the InChIKey RRELDGDKULRRDM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RRELDGDKULRRDM
Search UniChem for chemical match using the InChIKey RRELDGDKULRRDM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RRELDGDKULRRDM
Comments
8c is a potent B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with a favourable pharmacokinetic profile for drug development [1].