AZD1678

Ligand id: 9679

Name: AZD1678

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 89.56
Molecular weight 350.96
XLogP 1.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2,3-dichloro-N-(5-fluoro-3-methoxypyrazin-2-yl)benzenesulfonamide
Synonyms
AZD-1678 | compound 49 [PMID: 28947948]
Database Links
GtoPdb PubChem SID 348353638
PubChem CID 23585443
Search Google for chemical match using the InChIKey NWSUDJQTTGDPIR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NWSUDJQTTGDPIR
Search UniChem for chemical match using the InChIKey NWSUDJQTTGDPIR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NWSUDJQTTGDPIR
Comments
AZD1678 is a potent and bioavailable aminopyrazine sulfonamide CCR4 receptor antagonist discovered in a high-throughput screening/synthesis campaign [1]