solcitinib

Ligand id: 9697

Name: solcitinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 79.6
Molecular weight 389.19
XLogP 3.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[5-[4-(3,3-dimethylazetidine-1-carbonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
International Nonproprietary Names
INN number INN
10047 solcitinib
Synonyms
compound 1 [WO2010149771] | GLPG-0778 | GLPG0778 | GSK2586184
Comments
Solcitinib is a Janus kinase 1 (JAK1)-selective inhibitor, with anti-inflammatory activity [1].
Database Links
BitterDB Ligand 128101
CAS Registry No. 1206163-45-2 (source: WHO INN record)
ChEMBL Ligand CHEMBL3301606
GtoPdb PubChem SID 348353656
PubChem CID 44603362
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