isunakinra

Ligand id: 9704

Name: isunakinra

Classification
Compound class Peptide or derivative
International Nonproprietary Names
INN number INN
10091 isunakinra
Synonyms
EBI-005
Comments
Isunakinra (EBI-005) is a fusion protein containing domains from IL-1β and IL-1 receptor antagonist (IL-1Ra or anakinra) [3]. It potently blocks IL-1R1 signalling, with higher affinity than anakinra. It was developed as a topical therapy for inflammatory diseases of the ocular surface.
Database Links
ChEMBL Ligand CHEMBL3545190
DrugBank Ligand DB12373
GtoPdb PubChem SID 348353663
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