BIRT 377

Ligand id: 9720

Name: BIRT 377

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 40.62
Molecular weight 439.97
XLogP 4.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione
Synonyms
BIRT-377
Comments
BIRT 377 is an orally active inhibitor of the LFA-1/ICAM-1 interaction [1].
Database Links
BindingDB Ligand 50154496
ChEMBL Ligand CHEMBL367808
GtoPdb PubChem SID 348353679
PubChem CID 9803375
Search Google for chemical match using the InChIKey FJNJHZQMQRVZEE-GOSISDBHSA-N
Search Google for chemicals with the same backbone FJNJHZQMQRVZEE
Search UniChem for chemical match using the InChIKey FJNJHZQMQRVZEE-GOSISDBHSA-N
Search UniChem for chemicals with the same backbone FJNJHZQMQRVZEE

Product suppliers

Tocris
BIRT 377
Cat. No. 4776