pecazine

Ligand id: 9782

Name: pecazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 31.78
Molecular weight 310.15
XLogP 4.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Withdrawn drug? Yes
IUPAC Name
10-[(1-methylpiperidin-3-yl)methyl]phenothiazine
International Nonproprietary Names
INN number INN
523 pecazine
Synonyms
mepazine | nothiazine | Pacatal
Comments
Pecazine is a phenothiazine derivative that was historically used as an antipsychotic/tranquillizer, but use has replaced by newer drugs. Pecazine is also an allosteric inhibitor of MALT1 protease activity [1]. It may be used experimentally as the acetate or hydrochloride.
Database Links
BindingDB Ligand 50177661
ChEMBL Ligand CHEMBL395110
GtoPdb PubChem SID 354702255
PubChem CID 6075
Search Google for chemical match using the InChIKey CBHCDHNUZWWAPP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CBHCDHNUZWWAPP
Search PubMed clinical trials pecazine
Search PubMed titles pecazine
Search PubMed titles/abstracts pecazine
Search UniChem for chemical match using the InChIKey CBHCDHNUZWWAPP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone CBHCDHNUZWWAPP