AZD9567

Ligand id: 9812

Name: AZD9567

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 76.46
Molecular weight 494.21
XLogP 5.53
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2,2-difluoro-N-[(1R,2S)-3-methyl-1-[1-(1-methyl-6-oxopyridin-3-yl)indazol-5-yl]oxy-1-phenylbutan-2-yl]propanamide
Synonyms
AZD 9567 | AZD-9567 | compound 15 [PMID: 29424542] | example 1 [WO2016046260A1] [2]
Comments
AZD9567 is a synthetic, selective glucocorticoid receptor (GR) partial agonist [1]. It was designed to offer an improved side-effect profile compared to conventional full agonist GR anti-inflammatory dugs. AZD9567 is one of the chemical structures claimed in patent WO2016046260A1 [2].
Database Links
GtoPdb PubChem SID 354702284
PubChem CID 121248172
RCSB PDB Ligand B9W
Search Google for chemical match using the InChIKey ZQFNDBISEYQVRR-LOSJGSFVSA-N
Search Google for chemicals with the same backbone ZQFNDBISEYQVRR
Search UniChem for chemical match using the InChIKey ZQFNDBISEYQVRR-LOSJGSFVSA-N
Search UniChem for chemicals with the same backbone ZQFNDBISEYQVRR