ozagrel

Ligand id: 9866

Name: ozagrel

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 55.12
Molecular weight 228.09
XLogP 2.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (China and Japan only)
IUPAC Name
3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid
International Nonproprietary Names
INN number INN
5918 ozagrel
Synonyms
Cataclot® | KCT-0809 | OKY-046 | Pulmoza®
Comments
Ozagrel is a thromboxane A synthetase (CYP5A1; TBXAS1) inhibitor that has anti-inflammatory action [2]. Note that some of the bioactivity data for ozagrel relate to use of ozagrel sodium or ozagrel hydrochloride.
Database Links
BindingDB Ligand 50017896
CAS Registry No. 82571-53-7 (source: WHO INN record)
ChEMBL Ligand CHEMBL11662
GtoPdb PubChem SID 363894160
PubChem CID 5282440
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