Compound class:
Peptide or derivative
Comment: Fully active INSL3 is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 34) and A chain (residue 116), and the second between B chain (residue 46) and A chain (residue 129). For details of the structure of this ligand see the ligand pages for the non-radiolabelled form and its subunits. [125I]INSL3 is synthesised by adding radiolabelled iodine to the A-chain subunit, either to tyrosine at position 9 or 26
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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