BRL-15572

Ligand id: 10

Name: BRL-15572

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 26.71
Molecular weight 406.18
XLogP 8.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT1D receptor Agonist Partial agonist 7.9 pKi - 1
pKi 7.9 [1]
5-HT1A receptor Agonist Partial agonist 7.7 pKi - 1
pKi 7.7 [1]
5-HT2B receptor Agonist Partial agonist 7.4 pKi - 1
pKi 7.4 [1]
5-HT2A receptor Agonist Full agonist 6.6 pKi - 1
pKi 6.6 [1]
5-HT2C receptor Agonist Partial agonist 6.2 pKi - 1
pKi 6.2 [1]
5-HT1B receptor Agonist Partial agonist 6.1 pKi - 1
pKi 6.1 [1]
5-HT1F receptor Agonist Partial agonist 6.0 pKi - 1
pKi 6.0 [1]
5-HT6 receptor Agonist Partial agonist 5.9 pKi - 1
pKi 5.9 [1]
5-ht1e receptor Agonist Partial agonist 5.2 pKi - 1
pKi 5.2 [1]