BRL-15572

Ligand id: 10

Name: BRL-15572

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 26.71
Molecular weight 406.18
XLogP 8.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT1D receptor Hs Agonist Partial agonist 7.9 pKi - 1
pKi 7.9 [1]
5-HT1A receptor Hs Agonist Partial agonist 7.7 pKi - 1
pKi 7.7 [1]
5-HT2B receptor Hs Agonist Partial agonist 7.4 pKi - 1
pKi 7.4 [1]
5-HT2A receptor Hs Agonist Full agonist 6.6 pKi - 1
pKi 6.6 [1]
5-HT2C receptor Hs Agonist Partial agonist 6.2 pKi - 1
pKi 6.2 [1]
5-HT1B receptor Hs Agonist Partial agonist 6.1 pKi - 1
pKi 6.1 [1]
5-HT1F receptor Hs Agonist Partial agonist 6.0 pKi - 1
pKi 6.0 [1]
5-HT6 receptor Hs Agonist Partial agonist 5.9 pKi - 1
pKi 5.9 [1]
5-ht1e receptor Hs Agonist Partial agonist 5.2 pKi - 1
pKi 5.2 [1]