benidipine

Ligand id: 10159

Name: benidipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 111.01
Molecular weight 505.22
XLogP 5.41
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Cav1.2 Hs Channel blocker Antagonist 5.3 pIC50 - 1
pIC50 5.3 (IC50 4.9x10-6 M) [1]
Description: Inhibition of human L-type calcium channel Cav1.2 in Xenopus oocyte, measured using 2-electrode voltage-clamp.