CGP 35348

Ligand id: 1069

Name: CGP 35348

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 91.59
Molecular weight 225.11
XLogP -0.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Antagonist Antagonist 4.4 pKi - 4
pKi 4.4 [4]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Antagonist Antagonist 5.4 pIC50 - 1
pIC50 5.4 [1]
GABAB1 Antagonist Antagonist 4.6 – 4.8 pIC50 - 2-3
pIC50 4.6 – 4.8 [2-3]
Ligand mentioned in the following text fields