[125I]CGP 64213

Ligand id: 1076

Name: [125I]CGP 64213    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Topological polar surface area 166
Molecular weight 646.13
XLogP 3.45
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Rn Antagonist Antagonist 9.0 pKd - 1
pKd 9.0 (Kd 1x10-9 M) [1]
GABAB1 Rn Antagonist Antagonist 8.9 pKd - 2
pKd 8.9 [2]