ranitidine

Ligand id: 1234

Name: ranitidine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: ranitidine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 108.88
Molecular weight 314.14
XLogP 2.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
H2 receptor Antagonist Antagonist 7.1 pKi - 2
pKi 7.1 (Ki 7.94x10-8 M) [2]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
H2 receptor Antagonist Antagonist 6.2 pKi - 1
pKi 6.2 (Ki 6.31x10-7 M) [1]
Ligand mentioned in the following text fields