ATC0065

Ligand id: 1304

Name: ATC0065

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 62.31
Molecular weight 551.15
XLogP 6.84
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
MCH1 receptor Hs Antagonist Antagonist 7.8 – 7.9 pKi - 1
pKi 7.8 – 7.9 [1]
MCH2 receptor Hs Antagonist Antagonist 5.8 – 5.9 pIC50 - 1
pIC50 5.8 – 5.9 [1]