[125I]NDP-MSH   Click here for help

GtoPdb Ligand ID: 1326

Synonyms: [125I]-NDP-MSH | [125I][Nle4,dPhe7]α-MSH
 Ligand is labelled  Ligand is radioactive
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Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
MC3 receptor Hs Agonist Full agonist 9.7 pKd - 1
pKd 9.7 (Kd 2x10-10 M) [1]
MC1 receptor Hs Agonist Full agonist 9.5 pKd - 1
pKd 9.5 (Kd 3.3x10-10 M) [1]
MC4 receptor Hs Agonist Full agonist 8.4 – 8.9 pKd - 1-2
pKd 8.4 – 8.9 (Kd 4x10-9 – 1.2x10-9 M) [1-2]
MC5 receptor Hs Agonist Full agonist 8.6 pKd - 1
pKd 8.6 (Kd 2.8x10-9 M) [1]