Ro67-4853

Ligand id: 1387

Name: Ro67-4853

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 64.63
Molecular weight 325.13
XLogP 4.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
mGlu1 receptor Rn Allosteric modulator Positive 5.1 pKi - 1
pKi 5.1 (Ki 7.94x10-6 M) [1]