eglumegad

Ligand id: 1393

Name: eglumegad

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 100.62
Molecular weight 185.07
XLogP -3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu3 receptor Agonist Full agonist 8.9 pKi - 4
pKi 8.9 [4]
mGlu2 receptor Agonist Full agonist 6.9 pKi - 4
pKi 6.9 [4]
mGlu8 receptor Agonist Full agonist 5.1 pEC50 - 6
pEC50 5.1 [6]
mGlu6 receptor Agonist Full agonist 5.5 pIC50 - 7
pIC50 5.5 [7]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu2 receptor Agonist Full agonist 7.8 – 7.9 pKi - 2,10
pKi 7.8 – 7.9 [2,10]
mGlu3 receptor Agonist Full agonist 7.3 pKi - 10
pKi 7.3 [10]
Ligand mentioned in the following text fields