eGlu

Ligand id: 1400

Name: eGlu

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 100.62
Molecular weight 175.08
XLogP -2.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu3 receptor Antagonist Antagonist 5.4 pKi - 2
pKi 5.4 [2]
mGlu2 receptor Antagonist Antagonist 4.4 – 4.6 pKi - 1-2
pKi 4.4 – 4.6 [1-2]
Ligand mentioned in the following text fields