Ligand id: 1407

Name: (S)-3,4-DCPG

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 137.92
Molecular weight 239.04
XLogP -2.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
mGlu8 receptor Hs Agonist Full agonist 7.5 pEC50 - 1
pEC50 7.5 [1]
mGlu6 receptor Hs Agonist Full agonist 5.4 pEC50 - 1
pEC50 5.4 (EC50 3.98x10-6 M) [1]
mGlu4 receptor Hs Agonist Full agonist 5.1 pEC50 - 1
pEC50 5.1 [1]