Ligand id: 1408

Name: ACPT-I

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 137.92
Molecular weight 217.06
XLogP -4.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu4 receptor Agonist Full agonist 5.1 pEC50 - 1
pEC50 5.1 [1]
mGlu8 receptor Agonist Partial agonist 5.1 pEC50 - 2
pEC50 5.1 [2]
mGlu6 receptor Agonist Full agonist 4.7 pIC50 -
pIC50 4.7