dimethyltryptamine

Ligand id: 141

Name: dimethyltryptamine

Abbreviated name: DMT

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 19.03
Molecular weight 188.13
XLogP 2.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT6 receptor Agonist Full agonist 7.2 pKi - 1
pKi 7.2 [1]
5-HT1D receptor Agonist Full agonist 7.0 – 7.3 pKi - 2
pKi 7.0 – 7.3 [2]