Ligand id: 1418

Name: (S)-4CPG

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 100.62
Molecular weight 195.05
XLogP -1.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at Rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu1 receptor Antagonist Antagonist 5.4 pKi - 1
pKi 5.4 [1]
mGlu5 receptor Antagonist Antagonist 4.6 pIC50 - 2
pIC50 4.6 [2]