BIBP3226

Ligand id: 1485

Name: BIBP3226

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 13
Topological polar surface area 142.83
Molecular weight 473.24
XLogP 6.32
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Y1 receptor Hs Antagonist Antagonist 8.1 – 9.3 pKi - 2,8
pKi 8.1 – 9.3 (Ki 7.6x10-9 – 4.7x10-10 M) [2,8]
Y1 receptor Rn Antagonist Antagonist 7.9 – 8.5 pKi - 2-3,5
pKi 7.9 – 8.5 [2-3,5]
NPFF1 receptor Hs Antagonist Antagonist 7.0 – 7.8 pKi - 1,4,7
pKi 7.0 – 7.8 [1,4,7]
NPFF2 receptor Hs Antagonist Antagonist 5.9 – 7.1 pKi - 1,6
pKi 5.9 – 7.1 [1,6]
Ligand mentioned in the following text fields