BIBO3304

Ligand id: 1528

Name: BIBO3304

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 6
Rotatable bonds 16
Topological polar surface area 177.72
Molecular weight 529.28
XLogP 5.59
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Y1 receptor Antagonist Antagonist 9.5 pIC50 - 2
pIC50 9.5 (IC50 3.8x10-10 M) [2]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Y1 receptor Antagonist Antagonist 9.7 pIC50 - 1
pIC50 9.7 [1]