(-)-pentazocine

Ligand id: 1606

Name: (-)-pentazocine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 23.47
Molecular weight 285.21
XLogP 4.09
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
μ receptor Agonist Partial agonist 8.4 pKi - 1
pKi 8.4 [1]
κ receptor Agonist Partial agonist 7.8 – 8.6 pKi - 1-2
pKi 7.8 – 8.6 [1-2]
δ receptor Agonist Full agonist 7.3 pKi - 1
pKi 7.3 [1]
Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
sigma non-opioid intracellular receptor 1 Antagonist Antagonist - - -
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