dynorphin A-(1-8)

Ligand id: 1621

Name: dynorphin A-(1-8)

Species: Human, Mouse, Rat

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
δ receptor
κ receptor
μ receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
κ receptor Hs Agonist Full agonist 8.0 – 9.9 pKi - 1-3,5
pKi 8.0 – 9.9 [1-3,5]
δ receptor Hs Agonist Partial agonist 8.4 pKi - 3
pKi 8.4 [3]
μ receptor Hs Agonist Full agonist 8.4 pKi - 3
pKi 8.4 [3]
κ receptor Mm Agonist Full agonist 9.7 pIC50 - 4
pIC50 9.7 [4]