brolamfetamine

Ligand id: 163

Name: brolamfetamine

Abbreviated name: DOB

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 44.48
Molecular weight 273.04
XLogP 2.07
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT2A receptor Hs Agonist Full agonist 8.9 – 9.2 pKi - 4-5
pKi 8.9 – 9.2 [4-5]
5-HT2C receptor Hs Agonist Full agonist 6.8 – 8.9 pKi - 1,4-5
pKi 6.8 – 8.9 [1,4-5]
5-HT2A receptor Rn Agonist Full agonist 7.8 pKi - 2
pKi 7.8 [2]
5-HT2B receptor Hs Agonist Full agonist 7.4 – 7.6 pKi - 4-5
pKi 7.4 – 7.6 [4-5]
5-HT2C receptor Rn Agonist Full agonist 6.6 pKi - 3
pKi 6.6 [3]